Multidimensional analysis of the gut microbiome, including the virome,archaeome, bacteriome, and mycobiome,along with genetic and immunological profiling in adult IBD patients: Correlation with disease pathogenesis and response to biological treatment
Project manager: dr Agnieszka Krawczyk
Implementation period: 2026-2030
Project type: OPUS 29 Project description
Evaluation of the utility of NGS sequencing and microbiome-DynaMAP profiling for the analysis of microbiota composition abnormalities and identification of pathogens in the course of diarrhea of undetermined etiology in patients with blood cancers
Analysis of changes in the composition of the bacterial gut microbiota in obese rats after transcranial direct current stimulation - a pilot study using a next-generation sequencing method
Project manager: dr Katarzyna Talaga-Ćwiertnia
Implementation period: 2023-2024
Project type: Miniatura 7 Project description
Evaluation of the brain microbiome and proteome as well as the role of fecal microbiota transplantation (FMT) in schizophrenia - studies in a methylazoxymethanol acetate (MAM-E17) rat model
Metagenomic analysis of the bacteriobiom and mycobiom of the gastrointestinal tract of children and adolescents with celiac disease and their healthy siblings, as well as healthy children with HLA DQ2 and/or DQ8 antigen
Project manager: dr hab. Tomasz Gosiewski, prof. UJ
Implementation period: 2018 – 2023
Project type: Sonata Bis 7 Project description
Characterization of immunogenic proteins of Streptococcus agalactiae with identification of epitope recognized by cord blood protective antibodies
Project manager: dr hab. Monika Brzychczy - Włoch, prof. UJ
Implementation period: 2014 – 2018
Project type: Opus 5
Raman spectroscopy as a diagnostic tool for identifying atypical and anaerobic bacteria of the reproductive system: a pilot study on microbiological risk factors for infertility
Project leader: dr Agnieszka Gonet-Surówka
Implementation period: 2025 - 2027
Evaluation of the effectiveness of culture-based methods in the detection of bloodstream infections in patients
Project leader: professor Tomasz Gosiewski
Implementation period: 2025 - 2026
Optimization of the preparation of biological samples for proteomic studies and correlation of the proteome with the composition of the microbiome determined using the NGS sequencing method
Project leader: professor Monika Brzychczy-Włoch
Implementation period: 2024 - 2025
Evaluation of metabolic activity of early bacterial biofilm using fluorimetric method on different biomaterial surfaces
Research on the application of innovative methods to control bacterial biofilms on polyethylene and polyvinyl tracheostomy tubes in patients after a tracheostomy procedure
Project manager: dr hab. Monika Brzychczy - Włoch, prof. UJ
Implementation period: 2020 – 2021
Evaluation of biofilm formation by clinical isolates of Klebsiella pneumoniae on biomaterials used in the manufacture of tracheostomy tubes
Quantitative analysis of selected species of bacterial and fungal gastrointestinal microbiome in pharmacologically induced schizophrenia in a rat model
Project manager: dr Dominika Salamon
Implementation period: 2019 – 2021
Significance of mixed viral infections in non-melanoma HPV-associated skin cancers
Genetic and epigenetic changes of papillomaviruses with high oncogenic potential in the context of the ability to integrate the virus into the host cell and mechanisms of tumorigenesis
Phenotypic and genotypic characterization of herpes virus strains classified into separate species, HSV-1 and HSV-2
Project manager: dr hab. Barbara Zawilińska
Implementation period: 2018– 2022
Quantitative comparative analysis of selected colonic anaerobic bacterial species in children with Crohn's disease in a group of patients treated with nutritional therapy and in a group of patients undergoing biological therapy
Project manager: dr Dominika Salamon
Implementation period: 2017 - 2018
Quantitative evaluation of Candida in a group of children with Crohn's disease treated with nutritional and biological therapy compared to children with Crohn's disease
Project manager: dr hab. Tomasz Gosiewski, prof. UJ
Implementation period: 2017 - 2018
Evaluation of in vitro antiviral activity of lipoic acid, 2-mercaptoethanesulfonic acid, N-acetylacetic acid, and ellagic acid against selected DNA and RNA viruses
Assessment of the composition of women's reproductive tract flora analyzed in successive three trimesters of pregnancy using a next-generation sequencing method
Project manager: dr hab. Monika Brzychczy - Włoch
Implementation period: 2017 - 2018
Assessment of the incidence of acne lesions with Propionibacterium acnes etiology in 2008-2012 in Malopolska region
Studies on biofilm formation and adherence to established cell lines of Streptococcus agalactiae clinical isolates from urinary tract infections from adult patients
Quantitative comparative analysis of selected gastrointestinal archaeon species among patients with newly diagnosed celiac disease and analysis of the dynamics of changes over time, during the gluten-free diet
