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Evaluation of the utility of NGS sequencing and microbiome-DynaMAP profiling for the analysis of microbiota composition abnormalities and identification of pathogens in the course of diarrhea of undetermined etiology in patients with blood cancers

Project manager: dr Agnieszka Sroka-Oleksiak
Implementation period: 2023-2024
Project type: Miniatura 7
Project description

 

Analysis of changes in the composition of the bacterial gut microbiota in obese rats after transcranial direct current stimulation - a pilot study using a next-generation sequencing method

Project manager: dr Katarzyna Talaga-Ćwiertnia
Implementation period: 2023-2024
Project type: Miniatura 7
Project description

 

Evaluation of the brain microbiome and proteome as well as the role of fecal microbiota transplantation (FMT) in schizophrenia - studies in a methylazoxymethanol acetate (MAM-E17) rat model

Project manager: dr Dominika Salamon
Implementation period: 2022 – 2025
Project type: Sonata 17
Project description

 

Metagenomic analysis of the gut archeobiom and mycobiom of children with Crohn's disease compared to healthy subjects

Project manager: mgr Agnieszka Krawczyk
Implementation period: 2020 – 2023
Project type: Preludium 17
Project description

 

Rats, schizophrenia, and the gut microbiome of bacteria and fungi - a pilot study using Next Generation Sequencing (NGS)

Project manager: dr Dominika Salamon
Implementation period: 2019 – 2021
Project type: Miniatura 3
Project description

 

Metagenomic analysis of the bacteriobiom and mycobiom of the gastrointestinal tract of children and adolescents with celiac disease and their healthy siblings, as well as healthy children with HLA DQ2 and/or DQ8 antigen

Project manager: dr hab. Tomasz Gosiewski, prof. UJ
Implementation period: 2018 – 2023
Project type: Sonata Bis 7
Project description

 

Characterization of immunogenic proteins of Streptococcus agalactiae with identification of epitope recognized by cord blood protective antibodies

Project manager: dr hab. Monika Brzychczy - Włoch, prof. UJ
Implementation period: 2014 – 2018
Project type: Opus 5

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Models of multispecialty in-hospital and out-of-hospital care for patients with SARS-CoV-2 infection

Project manager (microbiology): dr hab. Tomasz Gosiewski
Implementation period: 2020 – 2021
Subproject title: Badania nad diagnostyką laboratoryjną zakażeń wywołanych przez wirus SARS-CoV-2 w przebiegu choroby COVID-19
Project type: Wsparcie szpitali jednoimiennych w walce z rozprzestrzenianiem się zakażenia wirusem SARS-CoV-2 oraz w leczeniu COVID-19
Project description

 

Innovative diagnostic test for the detection of antigens of selected species of bacteria that cause mastitis in cattle

Project manager: dr Anna Dobrut
Implementation period: 2020 - 2023
Project type: Lider
Project description

 

Innovative diagnostic test for detecting Streptococcus agalactiae infection and carriage among pregnant women

Project manager: prof. dr hab. Monika Brzychczy – Włoch
Implementation period: 2017 - 2022
Project type: Tango 2

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Development of FISH probes for in situ detection of microorganisms in a two-sided labeling system using an external universal oligonucleotide

Project manager: professor Tomasz Gosiewski
Implementation period: 2023 – 2024
Project description

 

Evaluation of the intestinal archeobiome in schizophrenia - a study in a rat model

Project manager: dr Dominika Salamon
Implementation period: 2023 – 2024
Project description

 

Application of next-generation sequencing method to analyze intestinal mycobiotics in obese rats subjected to transcranial direct current stimulation

Project manager: dr Katarzyna Talaga-Ćwiertnia
Implementation period: 2022 – 2023
Project description
 

Development and standardization of methods for the study of the human virome using the next-generation sequencing (NGS) method

Project manager: prof. dr hab. Monika Brzychczy-Włoch
Implementation period: 2022 – 2023
Project description

 

Development of a method for bacterial species identification using Raman spectroscopy and artificial intelligence - pilot study

Project manager: dr Agnieszka Sroka-Oleksiak
Implementation period: 2022 – 2023
Project description

 

Effect of disulfiram (DSF) on the proliferation and growth of atypical bacteria of the genus Ureaplasma (U. urealyticum, U. parvum)

Project manager: dr Małgorzata Biernat - Sudolska
Implementation period: 2022 – 2023
Project description

 

Bacterial RNA - a molecular biomarker in active bloodstream infections in patients with sepsis

Project manager: dr Agnieszka Sroka-Oleksiak
Implementation period: 2020 – 2021
Project description

 

Evaluation of the antimicrobial activity of lipoic acid against atypical bacteria of the family Mycobacteriaceae

Project manager: dr Małgorzata Biernat - Sudolska
Implementation period: 2020 – 2021
Project description

 

Research on the application of innovative methods to control bacterial biofilms on polyethylene and polyvinyl tracheostomy tubes in patients after a tracheostomy procedure

Project manager: dr hab. Monika Brzychczy - Włoch, prof. UJ
Implementation period: 2020 – 2021

 

Evaluation of biofilm formation by clinical isolates of Klebsiella pneumoniae on biomaterials used in the manufacture of tracheostomy tubes

Project manager: mgr Dorota Ochońska
Implementation period: 2020 – 2021
Project description

 

Quantitative analysis of selected species of bacterial and fungal gastrointestinal microbiome in pharmacologically induced schizophrenia in a rat model

Project manager: dr Dominika Salamon
Implementation period: 2019 – 2021

 

Significance of mixed viral infections in non-melanoma HPV-associated skin cancers

Project manager: mgr Jolanta Kopeć
Implementation period: 2019 - 2020
Project description

 

Screening negative blood samples for the possibility of trace bacteria using a rapid FISH identification method

Project manager: mgr Joanna Sobońska
Implementation period: 2019 - 2020

 

Genetic and epigenetic changes of papillomaviruses with high oncogenic potential in the context of the ability to integrate the virus into the host cell and mechanisms of tumorigenesis

Project manager: dr hab. Sława Szostek
Implementation period: 2018 - 2022

 

Phenotypic and genotypic characterization of herpes virus strains classified into separate species, HSV-1 and HSV-2

Project manager: dr hab. Barbara Zawilińska
Implementation period: 2018– 2022

 

Quantitative comparative analysis of selected colonic anaerobic bacterial species in children with Crohn's disease in a group of patients treated with nutritional therapy and in a group of patients undergoing biological therapy

Project manager: dr Dominika Salamon
Implementation period: 2017 - 2018

 

Quantitative evaluation of Candida in a group of children with Crohn's disease treated with nutritional and biological therapy compared to children with Crohn's disease

Project manager: dr hab. Tomasz Gosiewski, prof. UJ
Implementation period: 2017 - 2018

 

Evaluation of in vitro antiviral activity of lipoic acid, 2-mercaptoethanesulfonic acid, N-acetylacetic acid, and ellagic acid against selected DNA and RNA viruses

Project manager: dr Małgorzata Biernat - Sudolska
Implementation period: 2017 - 2018

 

Assessment of the composition of women's reproductive tract flora analyzed in successive three trimesters of pregnancy using a next-generation sequencing method

Project manager: dr hab. Monika Brzychczy - Włoch
Implementation period: 2017 - 2018

 

Assessment of the incidence of acne lesions with Propionibacterium acnes etiology in 2008-2012 in Malopolska region

Project manager: mgr Joanna Sobońska
Implementation period: 2017 - 2018

 

Genotyping of methicillin-resistant Staphylococcus aureus based on VNTR tandem repeat count variation study using MLVA method

Project manager: mgr Dorota Ochońska
Implementation period: 2017 - 2018

 

Studies on biofilm formation and adherence to established cell lines of Streptococcus agalactiae clinical isolates from urinary tract infections from adult patients

Project manager: dr hab. Monika Brzychczy-Włoch
Implementation period: 2015 - 2015

 

Genotypic variability of HPV with high oncogenic potential, and the forms of the viral genome in the process of cervical oncogenesis

Project manager: dr hab. Sława Szostek
Implementation period: 2015 - 2017

 

Specific immune response versus susceptibility to secondary herpesvirus infections

Project manager: dr hab. Barbara Zawilińska
Implementation period: 2015 - 2017

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Disorders of the oral microbiome in the course of selected cardiovascular diseases

Project manager: lek. dent. Barbara Brzychczy
Implementation period: 2022 – 2023
Project description

 

Analysis of changes in mycobiom composition over time in pediatric patients with Crohn's disease treated with anti-TNF-α antibodies

Project manager: mgr Agnieszka Krawczyk
Implementation period: 2022 - 2024
Project description

 

Research on the application of innovative methods to combat bacterial biofilms on polymeric implant materials

Project manager: mgr Kamil Drożdż
Implementation period: 2022 - 2023
Project description

 

Quantitative comparative analysis of selected gastrointestinal archaeon species among patients with newly diagnosed celiac disease and analysis of the dynamics of changes over time, during the gluten-free diet

Project manager: mgr Agnieszka Krawczyk
Implementation period: 2020 - 2021
Project description

 

Surface functionalization of polymeric biomaterials for dedicated implant applications

Project manager: lek med. lek dent. Łukasz Ścibik
Implementation period: 2019 - 2021

 

Evaluation of antimicrobial properties of copper alloys and selected metals by spectrofluorometric, microscopic and flow cytometry methods

Project manager: dr Agnieszka Sroka-Oleksiak
Implementation period: 2017 - 2018

 

Characterization of clinical Streptococcus agalactiae strains with MLSβ resistance phenotype using MLST typing

Project manager: dr Anna Dobrut
Implementation period: 2017 - 2018